March 2026 - Page 3 of 3 - THE SCIENCE NOTES

BCMA signaling pathway cartoon diagram showing NF-κB, PI3K-AKT, and MAPK pathways activated by BCMA in multiple myeloma cells

March 12, 2026March 24, 2026 Cancer Immunology

BCMA Signaling Pathway in Multiple Myeloma: Structure, Function and Therapeutic Targeting

BCMA signaling drives plasma cell survival in multiple myeloma through BAFF/APRIL activation of NF-κB, PI3K-AKT, and MAPK pathways. Read more

A scientific table comparing five bispecific antibodies. The top rows show structural designs: a BiTE (Blinatumomab) and four IgG-like structures (Mosunetuzumab, Epcoritamab, Glofitamab, and Odronextamab). The bottom panel illustrates "Mechanism & Pharmacokinetics," showing tissue penetration, T-cell engagement levels, and PK curves for each molecule.

March 12, 2026April 3, 2026 Cancer Immunology

Bispecific Antibodies in Cancer Immunotherapy

Explore the structural design, mechanism of action, and clinical applications of bispecific antibodies in cancer immunotherapy for targeted tumor killing. Read more

March 11, 2026March 24, 2026 Cancer

p53 Structure, Regulation, and Role in Cancer

Comprehensive review of p53 structure, regulation, activation pathways, and its role in cancer, including mechanisms of mutation and therapeutic targeting. Read more

Infographic showing Cryptosporidium parvum life cycle including oocyst excretion, transmission through contaminated water and food, excystation, multiplication, and autoinfection.

March 2, 2026March 30, 2026 Microbiology

Cryptosporidiosis: Causes, Life Cycle, Symptoms, Diagnosis, and Prevention

Learn about cryptosporidiosis caused by Cryptosporidium parvum: life cycle, watery diarrhea symptoms, diagnosis, treatment, and prevention tips for healthy and immunocompromised individuals. Read more

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