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THE SCIENCE NOTES
  • Diseases Guide
  • Cell and Molecular Biology
  • Anatomy and Physiology
  • Immunology
  • Protocols and Techniques
  • Food Science
  • Microbiology
  • Biotechnology
  • Biochemistry
  • Bacteriology
  • Cancer
  • Biology
  • News & Blogs
  • Contact Us
  • Privacy Policy

Author: Alisha G C

Hand drawn diagram showing amino acid structure with amino group, carboxyl group, R group and categorized list of amino acids including nonpolar, polar, acidic and basic types.
Posted on March 14, 2026 Biochemistry Biology

Amino Acids and Proteins: Structure, Peptide Bond Formation, and Biological Functions

Proteins are polymers of amino acids linked by peptide bonds. Learn about protein structure, amino acids, peptide bond, and functions. Read more

Infographic showing the mechanism of action of Teclistamab where the bispecific antibody binds BCMA on myeloma cells and CD3 on T cells to activate cytotoxic T-cell signaling and tumor cell killing.
Posted on March 12, 2026March 24, 2026 Cancer Immunology

Teclistamab in Multiple Myeloma: Mechanism, Structure and Clinical Trial Results

Teclistamab is a BCMA × CD3 bispecific antibody that redirects T cells to kill multiple myeloma cells in relapsed patients. Read more

Infographic showing BCMA-targeted therapies for multiple myeloma including bispecific antibody teclistamab, CAR-T cell therapy, and antibody-drug conjugate belantamab mafodotin.
Posted on March 12, 2026March 24, 2026 Cancer Immunology

BCMA-Targeted Therapies in Multiple Myeloma: Teclistamab vs CAR-T vs Antibody-Drug Conjugates

Compare BCMA therapies in multiple myeloma including Teclistamab, CAR-T therapy, and antibody-drug conjugates with mechanisms and clinical outcomes. Read more

BCMA signaling pathway cartoon diagram showing NF-κB, PI3K-AKT, and MAPK pathways activated by BCMA in multiple myeloma cells
Posted on March 12, 2026March 24, 2026 Cancer Immunology

BCMA Signaling Pathway in Multiple Myeloma: Structure, Function and Therapeutic Targeting

BCMA signaling drives plasma cell survival in multiple myeloma through BAFF/APRIL activation of NF-κB, PI3K-AKT, and MAPK pathways. Read more

A scientific table comparing five bispecific antibodies. The top rows show structural designs: a BiTE (Blinatumomab) and four IgG-like structures (Mosunetuzumab, Epcoritamab, Glofitamab, and Odronextamab). The bottom panel illustrates "Mechanism & Pharmacokinetics," showing tissue penetration, T-cell engagement levels, and PK curves for each molecule.
Posted on March 12, 2026April 3, 2026 Cancer Immunology

Bispecific Antibodies in Cancer Immunotherapy

Explore the structural design, mechanism of action, and clinical applications of bispecific antibodies in cancer immunotherapy for targeted tumor killing. Read more

Posted on March 11, 2026March 24, 2026 Cancer

p53 Structure, Regulation, and Role in Cancer

Comprehensive review of p53 structure, regulation, activation pathways, and its role in cancer, including mechanisms of mutation and therapeutic targeting. Read more

Infographic showing Cryptosporidium parvum life cycle including oocyst excretion, transmission through contaminated water and food, excystation, multiplication, and autoinfection.
Posted on March 2, 2026March 30, 2026 Microbiology

Cryptosporidiosis: Causes, Life Cycle, Symptoms, Diagnosis, and Prevention

Learn about cryptosporidiosis caused by Cryptosporidium parvum: life cycle, watery diarrhea symptoms, diagnosis, treatment, and prevention tips for healthy and immunocompromised individuals. Read more

Posted on February 28, 2026March 24, 2026 Microbiology

Amoebiasis Guide: Entamoeba Histolytica Life Cycle & Symptoms

Learn about Entamoeba histolytica: from its life cycle and transmission to symptoms of amoebiasis, laboratory diagnosis, and effective medical treatment. Read more

Proteins and amino acids showing 3D protein folding, peptide bond formation, and primary, secondary, tertiary, and quaternary structures, with labeled amino acid side chains.
Posted on February 21, 2026 Biochemistry

Proteins and Amino Acids: Structure, Function, and Biological Importance

Proteins are the molecular machines of life. Every cell in every living organism depends on proteins to survive, grow, communicate, and respond to the environment.... Read more

Infographic showing monocyte differentiation into pro-inflammatory M1 macrophages via GM-CSF and LPS/IFN-gamma, and anti-inflammatory M2 macrophages via M-CSF and IL-4, including 6-well plate culture steps and morphology differences.
Posted on February 21, 2026 Immunology

Monocyte Differentiation: Protocol for M1 and M2 Macrophage Polarization

In the sophisticated landscape of immunology, macrophages represent the frontline of innate immunity and the architects of tissue homeostasis. These cells are defined by their... Read more

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